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A key role for an impaired detoxification mechanism in the etiology and severity of autism spectrum disorders

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Moreover, iron is part of the prosthetic group of catalases, key antioxidant enzymes that counteract oxidative stress by catalyzing the reduction and detoxification of hydrogen peroxide

Since PKM encoded proteins are present on leukocytes and platelets, using whole blood to analyze for PK deficiency may result in false-negative results

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